Baldock, SJ;
Kevin, P;
Harper, GR;
Griffin, R;
Genedy, HH;
Fong, MJ;
Zhao, Z;
... Hardy, JG; + view all
(2023)
Creating 3D Objects with Integrated Electronics via Multiphoton Fabrication In Vitro and In Vivo.
Advanced Materials Technologies
, Article 2201274. 10.1002/admt.202201274.
(In press).
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Abstract
3D objects with integrated electronics are produced using an additive manufacturing approach relying on multiphoton fabrication (direct laser writing, (DLW)). Conducting polymer-based structures (with micrometer-millimeter scale features) are printed within exemplar matrices, including an elastomer (polydimethylsiloxane, (PDMS)) have been widely investigated for biomedical applications. The fidelity of the printing process in PDMS is assessed by optical coherence tomography, and the conducting polymer structures are demonstrated to be capable of stimulating mouse brain tissue in vitro. Furthermore, the applicability of the approach to printing structures in vivo is demonstrated in live nematodes (Caenorhabditis elegans). These results highlight the potential for such additive manufacturing approaches to produce next-generation advanced material technologies, notably integrated electronics for technical and medical applications (e.g., human-computer interfaces).
| Type: | Article |
|---|---|
| Title: | Creating 3D Objects with Integrated Electronics via Multiphoton Fabrication In Vitro and In Vivo |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1002/admt.202201274 |
| Publisher version: | https://doi.org/10.1002/admt.202201274 |
| Language: | English |
| Additional information: | © 2023 The Authors. Advanced Materials Technologies published by Wiley-VCH GmbH This is an open access article under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
| Keywords: | additive manufacturing, bioelectronics, conducting polymers, integrated electronics, neural electrodes |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Neuro, Physiology and Pharmacology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10168179 |
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