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Retention in care for type 2 diabetes management in Sub-Saharan Africa: A systematic review

Garrib, Anupam; Njim, Tsi; Adeyemi, Olukemi; Moyo, Faith; Halloran, Natalie; Luo, Huanyuan; Wang, Duolao; ... Jaffar, Shabbar; + view all (2023) Retention in care for type 2 diabetes management in Sub-Saharan Africa: A systematic review. Tropical Medicine & International Health 10.1111/tmi.13859. (In press). Green open access

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Abstract

OBJECTIVE: Diabetes prevalence has risen rapidly in Sub-Saharan Africa, but rates of retention in diabetes care are poorly understood. We conducted a systematic review and meta-analysis to determine rates of retention in care of persons with type 2 diabetes. METHODS: We searched MEDLINE, Global Health and CINAHL online databases for cohort studies and randomised control trials (RCTs) published up to 12 October 2021, that reported retention in or attrition from care for patients with type 2 diabetes in Sub-Saharan Africa. Retention was defined as persons diagnosed with diabetes who were alive and in care or with a known outcome, while attrition was defined as loss from care. RESULTS: From 6559 articles identified, after title and abstract screening, 209 articles underwent full text review. Forty six papers met the inclusion criteria, comprising 22,610 participants. Twenty one articles were of RCTs of which 8 trials had 1 year or more of follow-up and 25 articles were of non-randomised studies of which 19 had 12 months or more of follow-up. A total of 11 studies (5 RCTs and 6 non-randomised) were assessed to be of good quality. Sixteen RCTs were done in secondary or tertiary care settings. Their pooled retention rate (95% CI) was 80% (77%, 84%) in the control arm. Four RCTs had been done in primary care settings and their pooled retention rate (95% CI) was 53% (45%, 62%) in the control arm. The setting of one trial was unclear. For non-randomised studies, retention rates (95% CI) were 68% (62%, 75%) among 19 studies done in secondary and tertiary care settings, and 40% (33%, 49%) among the 6 studies done in primary care settings. CONCLUSION: Rates of retention in care of people living with diabetes are poor in primary care research settings.

Type: Article
Title: Retention in care for type 2 diabetes management in Sub-Saharan Africa: A systematic review
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1111/tmi.13859
Publisher version: https://doi.org/10.1111/tmi.13859
Language: English
Additional information: © 2023 The Authors Tropical Medicine & International Health Published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/).
Keywords: Sub-Saharan Africa, attrition, retention in care, retention rates, systematic review, type 2 diabetes
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health
URI: https://discovery.ucl.ac.uk/id/eprint/10165694
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