Galovic, M;
Al-Diwani, A;
Vivekananda, U;
Walker, MC;
Irani, SR;
Koepp, MJ;
(2023)
In Vivo N-Methyl-d-Aspartate Receptor (NMDAR) Density as Assessed Using Positron Emission Tomography During Recovery From NMDAR-Antibody Encephalitis.
JAMA Neurology
, 80
(2)
pp. 211-213.
10.1001/jamaneurol.2022.4352.
Preview |
Text
In Vivo N-Methyl-d-Aspartate Receptor (NMDAR) Density as Assessed Using Positron Emission Tomography During Recovery From NMDAR-Antibody Encephalitis.pdf Download (630kB) | Preview |
Abstract
N-methyl-d-aspartate receptor (NMDAR) autoantibodies are a common cause of autoimmune encephalitis. In vitro and animal studies indicated that NMDAR internalization is a major mechanism underlying NMDAR-antibody encephalitis, but direct support in humans is limited to a reduction of NMDAR staining in postmortem hippocampi.
Type: | Article |
---|---|
Title: | In Vivo N-Methyl-d-Aspartate Receptor (NMDAR) Density as Assessed Using Positron Emission Tomography During Recovery From NMDAR-Antibody Encephalitis |
Location: | United States |
Open access status: | An open access version is available from UCL Discovery |
DOI: | 10.1001/jamaneurol.2022.4352 |
Publisher version: | http://doi.org/10.1001/jamaneurol.2022.4352 |
Language: | English |
Additional information: | This version is the author accepted manuscript. For the purpose of Open Access, the author has applied a CC BY public copyright licence to any Author Accepted Manuscript (AAM) version arising from this submission |
Keywords: | Humans, Receptors, N-Methyl-D-Aspartate, Positron-Emission Tomography, Encephalitis, Autoantibodies, Anti-N-Methyl-D-Aspartate Receptor Encephalitis |
UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Clinical and Experimental Epilepsy |
URI: | https://discovery.ucl.ac.uk/id/eprint/10165660 |
Archive Staff Only
View Item |