Ramyead, S;
Denton, CP;
Orteu, CH;
Swale, V;
Mayor-Jerez, J;
Gardette, E;
(2023)
A purple plaque in a patient with systemic sclerosis.
Journal of Scleroderma and Related Disorders
, 8
(2)
NP1-NP3.
10.1177/23971983231152342.
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Abstract
We present the case of a 43-year old woman with anti-U3 ribonucleoprotein antibody-positive systemic sclerosis presenting with an enlarging purple plaque on the left upper arm. The skin was not sclerotic; however, there had been a cluster of long-standing telangiectases preceding the plaque. Histology and immunohistochemistry confirmed an angiosarcoma. There are five reported cases in the literature about angiosarcoma arising in the skin of patients with systemic sclerosis; however, to our knowledge, this is the first to have arisen from non-sclerotic skin. We would urge clinicians to adopt a high index of suspicion for atypical vascular tumours presenting in patients with systemic sclerosis.
| Type: | Article |
|---|---|
| Title: | A purple plaque in a patient with systemic sclerosis |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1177/23971983231152342 |
| Publisher version: | https://doi.org/10.1177/23971983231152342 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Inflammation |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10165128 |
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