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How well do covariates perform when adjusting for sampling bias in online COVID-19 research? Insights from multiverse analyses

Joyal-Desmarais, K; Stojanovic, J; Kennedy, EB; Enticott, JC; Boucher, VG; Vo, H; Košir, U; ... Levine, H; + view all (2022) How well do covariates perform when adjusting for sampling bias in online COVID-19 research? Insights from multiverse analyses. European Journal of Epidemiology , 37 pp. 1233-1250. 10.1007/s10654-022-00932-y. Green open access

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Abstract

COVID-19 research has relied heavily on convenience-based samples, which—though often necessary—are susceptible to important sampling biases. We begin with a theoretical overview and introduction to the dynamics that underlie sampling bias. We then empirically examine sampling bias in online COVID-19 surveys and evaluate the degree to which common statistical adjustments for demographic covariates successfully attenuate such bias. This registered study analysed responses to identical questions from three convenience and three largely representative samples (total N = 13,731) collected online in Canada within the International COVID-19 Awareness and Responses Evaluation Study (www.icarestudy.com). We compared samples on 11 behavioural and psychological outcomes (e.g., adherence to COVID-19 prevention measures, vaccine intentions) across three time points and employed multiverse-style analyses to examine how 512 combinations of demographic covariates (e.g., sex, age, education, income, ethnicity) impacted sampling discrepancies on these outcomes. Significant discrepancies emerged between samples on 73% of outcomes. Participants in the convenience samples held more positive thoughts towards and engaged in more COVID-19 prevention behaviours. Covariates attenuated sampling differences in only 55% of cases and increased differences in 45%. No covariate performed reliably well. Our results suggest that online convenience samples may display more positive dispositions towards COVID-19 prevention behaviours being studied than would samples drawn using more representative means. Adjusting results for demographic covariates frequently increased rather than decreased bias, suggesting that researchers should be cautious when interpreting adjusted findings. Using multiverse-style analyses as extended sensitivity analyses is recommended.

Type: Article
Title: How well do covariates perform when adjusting for sampling bias in online COVID-19 research? Insights from multiverse analyses
Location: Netherlands
Open access status: An open access version is available from UCL Discovery
DOI: 10.1007/s10654-022-00932-y
Publisher version: https://doi.org/10.1007/s10654-022-00932-y
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Science & Technology, Life Sciences & Biomedicine, Public, Environmental & Occupational Health, Sampling bias, Covariate adjustment, COVID-19, Multiverse analysis, Selection bias, Collider bias, PROPENSITY SCORE METHODS, SELECTION BIAS, CONVENIENCE SAMPLES, VOLUNTEER BIAS, REPRESENTATIVENESS, OVERADJUSTMENT
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences > Clinical, Edu and Hlth Psychology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Applied Health Research
URI: https://discovery.ucl.ac.uk/id/eprint/10165042
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