Lee, James C;
(2022)
Going deeper: molecular inflammatory scores in IBD.
Gut
10.1136/gutjnl-2022-328539.
(In press).
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Abstract
The management of IBD is evolving. Not long ago, symptomatic relief, or 'clinical remission' was the major treatment goal-if not the only goal-for most patients. However, the disconnect between inflammation and symptoms has been long recognised, and there is now abundant evidence that patients with silent inflammation, unsurprisingly, develop more disease-related complications than those with inactive disease.1 For this reason, current IBD management usually involves a 'treat-to-target' approach-a concept borrowed from rheumatology2-where objective measures of inflammation are used to ensure that treatment leads to resolution of inflammation as well as of symptoms.3
| Type: | Article |
|---|---|
| Title: | Going deeper: molecular inflammatory scores in IBD |
| Location: | England |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1136/gutjnl-2022-328539 |
| Publisher version: | http://dx.doi.org/10.1136/gutjnl-2022-328539 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | Gastroenterology & Hepatology, gene expression, IBD, inflammation, Life Sciences & Biomedicine, Science & Technology |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Inst for Liver and Digestive Hlth |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10164648 |
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