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Going deeper: molecular inflammatory scores in IBD

Lee, James C; (2022) Going deeper: molecular inflammatory scores in IBD. Gut 10.1136/gutjnl-2022-328539. (In press). Green open access

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Abstract

The management of IBD is evolving. Not long ago, symptomatic relief, or 'clinical remission' was the major treatment goal-if not the only goal-for most patients. However, the disconnect between inflammation and symptoms has been long recognised, and there is now abundant evidence that patients with silent inflammation, unsurprisingly, develop more disease-related complications than those with inactive disease.1 For this reason, current IBD management usually involves a 'treat-to-target' approach-a concept borrowed from rheumatology2-where objective measures of inflammation are used to ensure that treatment leads to resolution of inflammation as well as of symptoms.3

Type: Article
Title: Going deeper: molecular inflammatory scores in IBD
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1136/gutjnl-2022-328539
Publisher version: http://dx.doi.org/10.1136/gutjnl-2022-328539
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Gastroenterology & Hepatology, gene expression, IBD, inflammation, Life Sciences & Biomedicine, Science & Technology
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Inst for Liver and Digestive Hlth
URI: https://discovery.ucl.ac.uk/id/eprint/10164648
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