Lindner, Thomas;
Bolar, Divya S;
Achten, Eric;
Barkhof, Frederik;
Bastos-Leite, António J;
Detre, John A;
Golay, Xavier;
... on behalf of the ISMRM Perfusion Study Group; + view all
(2023)
Current state and guidance on arterial spin labeling perfusion MRI in clinical neuroimaging.
Magnetic Resonance in Medicine
10.1002/mrm.29572.
(In press).
Preview |
Text
Magnetic Resonance in Med - 2023 - Lindner - Current state and guidance on arterial spin labeling perfusion MRI in clinical.pdf - Published Version Download (3MB) | Preview |
Abstract
This article focuses on clinical applications of arterial spin labeling (ASL) and is part of a wider effort from the International Society for Magnetic Resonance in Medicine (ISMRM) Perfusion Study Group to update and expand on the recommendations provided in the 2015 ASL consensus paper. Although the 2015 consensus paper provided general guidelines for clinical applications of ASL MRI, there was a lack of guidance on disease-specific parameters. Since that time, the clinical availability and clinical demand for ASL MRI has increased. This position paper provides guidance on using ASL in specific clinical scenarios, including acute ischemic stroke and steno-occlusive disease, arteriovenous malformations and fistulas, brain tumors, neurodegenerative disease, seizures/epilepsy, and pediatric neuroradiology applications, focusing on disease-specific considerations for sequence optimization and interpretation. We present several neuroradiological applications in which ASL provides unique information essential for making the diagnosis. This guidance is intended for anyone interested in using ASL in a routine clinical setting (i.e., on a single-subject basis rather than in cohort studies) building on the previous ASL consensus review.
| Type: | Article |
|---|---|
| Title: | Current state and guidance on arterial spin labeling perfusion MRI in clinical neuroimaging |
| Location: | United States |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1002/mrm.29572 |
| Publisher version: | https://doi.org/10.1002/mrm.29572 |
| Language: | English |
| Additional information: | © 2023 The Authors. Magnetic Resonance in Medicine published by Wiley Periodicals LLC on behalf of International Society for Magnetic Resonance in Medicine. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
| Keywords: | arterial spin labeling, clinical routine ASL, perfusion |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Brain Repair and Rehabilitation |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10164469 |
Archive Staff Only
 |
View Item |
