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Reduced Presentation of Biliary Atresia During the COVID-19 Lockdown: A Population Based Observational Study

Arshad, A; Sutcliffe, A; Jain, V; Alizai, N; Rajwal, S; Kelly, DA; Dhawan, A; ... Baker, A; + view all (2023) Reduced Presentation of Biliary Atresia During the COVID-19 Lockdown: A Population Based Observational Study. Journal of Pediatric Gastroenterology and Nutrition , 76 (4) pp. 424-427. 10.1097/MPG.0000000000003706. Green open access

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Abstract

OBJECTIVE: The aim of this study was to assess whether there has been a change in presentations of Biliary Atresia (BA) in England and Wales during the first and second COVID-19 lockdowns (January - June 2020 and 2021). DESIGN: This population study assessed all confirmed cases of BA, from January 2020 to December 2021 across the 3 UK paediatric liver centers originating from England and Wales. Data was then compared to the incidence of confirmed BA cases from January - December 2017, 2018, and 2019. RESULTS: During January - June 2020 and 2021, there were only 8 and 12 presenting cases of BA in England and Wales, compared to 16, 13 and 18 for the same time periods in 2017, 2018 and 2019 respectively. This difference was significant in a two-sided t-test for 2020 (p = 0.035) but not for 2021 (p = 0.385). There was no difference in the mean days to Kasai procedure in January - June 2020 and 2021 compared to 2017-2019, however average time to Kasai after the lockdown periods was significantly higher. CONCLUSIONS: There was a significant reduction in the presenting cases of BA during the first COVID-19 lockdown, with an increased time for BA referrals after the pandemic lockdowns were lifted in England and Wales.

Type: Article
Title: Reduced Presentation of Biliary Atresia During the COVID-19 Lockdown: A Population Based Observational Study
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1097/MPG.0000000000003706
Publisher version: http://dx.doi.org/10.1097/MPG.0000000000003706
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Population, Policy and Practice Dept
URI: https://discovery.ucl.ac.uk/id/eprint/10163695
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