Thorley, Natasha;
Jones, Alexis;
Ciurtin, Coziana;
Castelino, Madhura;
Bainbridge, Alan;
Abbasi, Maaz;
Taylor, Stuart;
... Bray, Timothy JP; + view all
(2023)
Quantitative magnetic resonance imaging (qMRI) in Axial Spondyloarthritis.
The British Journal of Radiology
10.1259/bjr.20220675.
(In press).
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Abstract
Imaging, and particularly magnetic resonance imaging (MRI), plays a crucial role in the assessment of inflammation in rheumatic disease, and forms a core component of the diagnostic pathway in axial spondyloarthritis (axSpA). However, conventional imaging techniques are limited by image contrast being non-specific to inflammation and a reliance on subjective, qualitative reader interpretation. Quantitative MRI (qMRI) methods offer scope to address these limitations and improve our ability to accurately and precisely detect and characterise inflammation, potentially facilitating a more personalised approach to management. Here, we review qMRI methods and emerging quantitative imaging biomarkers (QIBs) for imaging inflammation in axSpA. We discuss the potential benefits as well as the practical considerations that must be addressed in the movement toward clinical translation of QIBs.
| Type: | Article |
|---|---|
| Title: | Quantitative magnetic resonance imaging (qMRI) in Axial Spondyloarthritis |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1259/bjr.20220675 |
| Publisher version: | https://doi.org/10.1259/bjr.20220675 |
| Language: | English |
| Additional information: | © 2022 The Authors. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 Unported License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10162888 |
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