Magalhães, Álvaro F;
Powner, Matthew W;
(2022)
Prebiotic triose glycolysis promoted by co-catalytic proline and phosphate in neutral water.
Chemical Communications
10.1039/d2cc05466c.
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Abstract
Proline and phosphate promote a near-quantitative aldol reaction between glycolaldehyde phosphate and formaldehyde at neutral pH in water. Our results demonstrate the important role of general acid-base catalysis in water and underscore the essential role that amino acid catalysis may have played in early evolution of life's core metabolic pathways.
| Type: | Article |
|---|---|
| Title: | Prebiotic triose glycolysis promoted by co-catalytic proline and phosphate in neutral water |
| Location: | England |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1039/d2cc05466c |
| Publisher version: | https://doi.org/10.1039/d2cc05466c |
| Language: | English |
| Additional information: | This article is licensed under a Creative Commons Attribution 3.0 Unported Licence (http://creativecommons.org/licenses/by/3.0/). |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > Dept of Chemistry |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10160811 |
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