UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Prebiotic triose glycolysis promoted by co-catalytic proline and phosphate in neutral water

Magalhães, Álvaro F; Powner, Matthew W; (2022) Prebiotic triose glycolysis promoted by co-catalytic proline and phosphate in neutral water. Chemical Communications 10.1039/d2cc05466c. Green open access

[thumbnail of d2cc05466c.pdf]
Preview
Text
d2cc05466c.pdf - Published Version

Download (613kB) | Preview

Abstract

Proline and phosphate promote a near-quantitative aldol reaction between glycolaldehyde phosphate and formaldehyde at neutral pH in water. Our results demonstrate the important role of general acid-base catalysis in water and underscore the essential role that amino acid catalysis may have played in early evolution of life's core metabolic pathways.

Type: Article
Title: Prebiotic triose glycolysis promoted by co-catalytic proline and phosphate in neutral water
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1039/d2cc05466c
Publisher version: https://doi.org/10.1039/d2cc05466c
Language: English
Additional information: This article is licensed under a Creative Commons Attribution 3.0 Unported Licence (http://creativecommons.org/licenses/by/3.0/).
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > Dept of Chemistry
URI: https://discovery.ucl.ac.uk/id/eprint/10160811
Downloads since deposit
30Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item