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Precision reimbursement for precision medicine: the need for patient-level decisions between payers, providers and pharmaceutical companies

Budhdeo, Sanjay; Ruhl, Michael; Agapow, Paul M; Sharma, Nikhil; Moss, Parker; (2021) Precision reimbursement for precision medicine: the need for patient-level decisions between payers, providers and pharmaceutical companies. Future Healthcare Journal , 8 (3) e695-e698. 10.7861/fhj.2021-0066. Green open access

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Abstract

Healthcare costs have been dramatically rising in developed economies worldwide. A key driver of cost increases has been high-cost drugs. The current model of reimbursement is not configured for drugs with uncertain outcomes. Future reimbursement will require better allocation of available healthcare system funds. Technological advancements have opened the door to a new type of outcomes-based reimbursement, enabling value exchange between payers and pharmaceutical companies, which we term precision reimbursement. Precision reimbursement extends beyond value-based contracts, with decisions at individual rather than aggregate level. For precision reimbursement to be adopted, there are data, computation and infrastructure requirements. All stakeholders benefit in moving to precision reimbursement for optimal resource allocation, risk sharing and, ultimately, improved outcomes. There are implementation challenges including cost, change management, information governance and development of surrogate markers. The overarching trend in medicine is toward personalised interventions, with precision reimbursement as the logical consequence.

Type: Article
Title: Precision reimbursement for precision medicine: the need for patient-level decisions between payers, providers and pharmaceutical companies
Open access status: An open access version is available from UCL Discovery
DOI: 10.7861/fhj.2021-0066
Publisher version: https://doi.org/10.7861/fhj.2021-0066
Language: English
Additional information: This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: precision medicine, reimbursement, value-based healthcare, stratified medicine
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Clinical and Movement Neurosciences
URI: https://discovery.ucl.ac.uk/id/eprint/10160376
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