Mehta, Dipal;
Jones, Daniel M;
Guha, Avirup;
MacCallum, Peter K;
Banerjee, Amitava;
Manisty, Charlotte;
Crake, Thomas;
... Ghosh, Arjun K; + view all
(2020)
DOACs for stroke prevention in patients with AF and cancer.
The British Journal of Cardiology
, 27
pp. 124-125.
10.5837/bjc.2020.036.
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Abstract
Stroke prophylaxis in atrial fibrillation is an important consideration in patients with cancer. However, there is little consensus on the choice of anticoagulation, due to the numerous difficulties associated with active cancer. Direct oral anticoagulants (DOACs) have been shown to be a promising option. Here, we conduct a simple cross-sectional analysis of 29 cancer patients receiving DOACs for stroke prophylaxis in atrial fibrillation at a tertiary-care institution in London. Our study demonstrates an encouraging efficacy and safety profile of DOACs used in this setting. We conclude by suggesting that, while DOACs may be useful, anticoagulation in cancer patients should continue to be individualised.
| Type: | Article |
|---|---|
| Title: | DOACs for stroke prevention in patients with AF and cancer |
| Location: | England |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.5837/bjc.2020.036 |
| Publisher version: | https://doi.org/10.5837/bjc.2020.036 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | atrial fibrillation, cancer, direct oral anticoagulants (DOACs) |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Health Informatics |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10159085 |
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