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Italian, European, And International Neuroinformatics Efforts: An Overview

Redolfi, Alberto; Archetti, Damiano; De Francesco, Silvia; Crema, Claudio; Tagliavini, Fabrizio; Lodi, Raffaele; Ghidoni, Roberta; ... D’Angelo, Egidio; + view all (2022) Italian, European, And International Neuroinformatics Efforts: An Overview. European Journal of Neuroscience 10.1111/ejn.15854. (In press). Green open access

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Abstract

Neuroinformatics is a research field that focuses on software tools capable of identifying, analysing, modelling, organising and sharing multi-scale neuroscience data. Neuroinformatics has exploded in the last two decades with the emergence of the Big-Data phenomenon, characterised by the so-called 3Vs (Volume, Velocity, and Variety), which provided neuroscientists with an improved ability to acquire and process data faster and more cheaply thanks to technical improvements in clinical, genomic, and radiological technologies. This situation has led to a "data deluge", as neuroscientists can routinely collect more study-data in a few days than they could in a year just a decade ago. To address this phenomenon, several neuroimaging-focused neuroinformatics platforms have emerged, funded by national or transnational agencies, with the following goals: (i) development of tools for archiving and organising analytical data (XNAT, REDCap, and LabKey); (ii) development of data-driven models evolving from reductionist approaches to multidimensional models (RIN, IVN, HBD, EuroPOND, E-DADS, GAAIN, BRAIN); and (iii) development of e-infrastructures to provide sufficient computational power and storage resources (neuGRID, HBP-EBRAINS, LONI, CONP). Although the scenario is still fragmented, there are technological and economical attempts at both national and international levels to introduce high standards for open and Findable, Accessible, Interoperable, and Reusable (FAIR) neuroscience worldwide.

Type: Article
Title: Italian, European, And International Neuroinformatics Efforts: An Overview
Location: France
Open access status: An open access version is available from UCL Discovery
DOI: 10.1111/ejn.15854
Publisher version: https://doi.org/10.1111/ejn.15854
Language: English
Additional information: Copyright © 2022 The Authors. European Journal of Neuroscience published by Federation of European Neuroscience Societies and John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
Keywords: Alzheimer’s Disease, Computational models, FAIR, International cooperation, Neuroinformatics
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Neuroinflammation
URI: https://discovery.ucl.ac.uk/id/eprint/10158692
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