UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Answers to common questions about COVID-19 vaccines in children with cancer

Caniza, Miguela A; Homsi, Maysam R; Bate, Jessica; Adrizain, Riyadi; Ahmed, Tarek; Alexander, Sarah; Bhattacharyya, Arpita; ... Pritchard-Jones, Kathy; + view all (2022) Answers to common questions about COVID-19 vaccines in children with cancer. Pediatric Blood & Cancer , 69 (12) , Article e29985. 10.1002/pbc.29985. Green open access

[thumbnail of Pritchard-Jones_COVID19VaxQA-Manuscript-Figs-TablesR1-20220814.pdf]
Preview
Text
Pritchard-Jones_COVID19VaxQA-Manuscript-Figs-TablesR1-20220814.pdf - Accepted Version

Download (506kB) | Preview

Abstract

Background: The SARS-CoV-2 outbreak in 2020 evolved into a global pandemic, and COVID-19 vaccines became rapidly available, including for pediatric patients. However, questions emerged that challenged vaccine acceptance and use. We aimed to answer these questions and give recommendations applicable for use in pediatric patients with cancer by healthcare professionals and the public. Methods: A 12-member global COVID-19 Vaccine in Pediatric Oncology Working Group made up of physicians and nurses from all world regions met weekly from March to July 2021. We used a modified Delphi method to select the top questions. The Working Group, in four-member subgroups, answered assigned questions by providing brief recommendations, followed by a discussion of the rationale for each answer. All Working Group members voted on each recommendation using a scale of 1 to 10, 10 being complete agreement. A “pass” recommendation corresponded to an agreement ≥7.5. Results: We selected 15 questions from 173 suggested questions. Based on existing published information, we generated answers for each question as recommendations. The overall average agreement for the 24 recommendations was 9.5 (95% CI 9.4–9.6). Conclusion: Top COVID-19 vaccine-related questions could be answered using available information. Reports on COVID-19 vaccination and related topics have been published at record speed, aided by available technology and the priority imposed by the pandemic; however, all efforts were made to incorporate emerging information throughout our project. Recommendations will be periodically updated on a dedicated website.

Type: Article
Title: Answers to common questions about COVID-19 vaccines in children with cancer
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1002/pbc.29985
Publisher version: https://doi.org/10.1002/pbc.29985
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Science & Technology, Life Sciences & Biomedicine, Oncology, Hematology, Pediatrics, COVID-19, infectious diseases, infection prevention, pediatric cancer, vaccines, VACCINATION, SARS-COV-2, RISK
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Biology and Cancer Dept
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
URI: https://discovery.ucl.ac.uk/id/eprint/10158682
Downloads since deposit
4Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item