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Occasions for laughter and dementia risk: Findings from a six-year cohort study

Wang, Yu; Shirai, Kokoro; Ohira, Tetsuya; Hirosaki, Mayumi; Kondo, Naoki; Takeuchi, Kenji; Yamaguchi, Chikae; ... Iso, Hiroyasu; + view all (2022) Occasions for laughter and dementia risk: Findings from a six-year cohort study. Geriatrics and Gerontology International , 22 (5) pp. 392-398. 10.1111/ggi.14371. Green open access

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Abstract

AIM: Currently, there is little evidence on the relationship between laughter and the risk of dementia, and since laughter is mainly a social behavior, we aimed to examine the association between various occasions for laughter and the risk of dementia in Japanese older adults. METHODS: We draw upon 6-year follow-up data from the Japan Gerontological Evaluation Study, including 12 165 independent older adults aged 65 years or over. Occasions for laughter were assessed using a questionnaire, while dementia was diagnosed using the standardized dementia scale of the long-term care insurance system in Japan. Cox proportional hazards models were estimated, yielding hazard ratios and 95% confidence intervals (CIs). RESULTS: The multivariable hazard ratio of dementia incidence for all participants in the groups for high versus low variety of occasions for laughter was 0.84 (95% CI: 0.72-0.98, P for trend <0.001). A greater variety of occasions for laughter was associated with a lower risk of dementia 0.78 (95% CI: 0.63-0.96, P for trend <0.001) among women, but was less pronounced for men, with significant associations only for the medium group. Laughing during conversations with friends, communicating with children or grandchildren, and listening to the radio were primarily associated with decreased risk. CONCLUSION: A greater variety of laughter occasions in individual and social settings was associated with a reduced risk of dementia. Geriatr Gerontol Int 2022; 22: 392–398.

Type: Article
Title: Occasions for laughter and dementia risk: Findings from a six-year cohort study
Location: Japan
Open access status: An open access version is available from UCL Discovery
DOI: 10.1111/ggi.14371
Publisher version: https://doi.org/10.1111/ggi.14371
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Cohort studies, dementia, laughter, older adults
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Behavioural Science and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
URI: https://discovery.ucl.ac.uk/id/eprint/10158341
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