Metcalfe, B;
Granger, N;
Prager, J;
Jabban, L;
Taylor, J;
Sadrafshari, S;
Donaldson, N;
(2021)
Urinary Bladder Innervation Within the Sacral Roots of a Sheep.
In:
Proceedings of the 10th International IEEE/EMBS Conference on Neural Engineering (NER) 2021.
(pp. pp. 605-608).
IEEE
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Abstract
Managing the urinary bladder after spinal cord injury is of primary importance because neurogenic dysfunction leads to life-threatening complications. Sacral Anterior Root Stimulators that control the bladder have been available for many years, however, these devices cannot sense the fullness of the bladder or detect the onset of reflex voiding. In order to address this fundamental limitation, this paper explores the possibility of recording the neural signals that encode bladder fullness from the sacral roots in sheep using extra-neural books. Stimulation of and recording from six roots (S1, S2 and S3 bilaterally) shows that efferent and afferent pathways seem to be co-located within roots, but also that simultaneous recording from multiple roots may be useful to enhance overall signal quality.
| Type: | Proceedings paper |
|---|---|
| Title: | Urinary Bladder Innervation Within the Sacral Roots of a Sheep |
| Event: | 10th International IEEE-EMBS Conference on Neural Engineering (NER) |
| Location: | Virtual Conference |
| Dates: | 4th-6th May 2021 |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1109/NER49283.2021.9441117 |
| Publisher version: | https://doi.org/10.1109/NER49283.2021.9441117 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions. |
| UCL classification: | UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng UCL > Provost and Vice Provost Offices > UCL BEAMS UCL |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10157360 |
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