Teräs, Tea;
Rovio, Suvi;
Pentti, Jaana;
Head, Jenny;
Kivimäki, Mika;
Stenholm, Sari;
(2022)
Association of sleep with cognitive function during retirement transition: The Whitehall II Study.
Sleep
10.1093/sleep/zsac237.
(In press).
![]() |
Text
zsac237.pdf - Accepted Version Access restricted to UCL open access staff until 28 September 2023. Download (937kB) |
Abstract
Study Objectives: Sleep duration and difficulties have been shown to associate with cognitive function. This study examined how changes in sleep and in cognitive function are associated during retirement transition. Methods: The study population consisted of 2,980 Whitehall II study participants, who retired during the follow-up, whose sleep was queried, and cognitive function measured (inductive reasoning and verbal memory) before and after retirement (follow-up 16 years). Using the last information on sleep before and the first after retirement, participants were categorized into constantly without (59%), increasing (13%), decreasing (11%), and constantly with (18%) sleep difficulties; and constantly short (26%), increasing (19%), decreasing (8.5%), and constantly mid-range (47%) sleep duration. Change in cognitive function during retirement transition was examined by sleep change groups using linear regression analyses with generalized estimating equations. Results: More pronounced decline in inductive reasoning during retirement transition was observed among participants with increasing sleep difficulties (-1.96, 95%CI -2.52 to -1.41) compared to those constantly without sleep difficulties (-1.25, 95%CI -1.52 to -0.98) and constantly with sleep difficulties (-1.26, 95%CI -1.75 to -0.92). Decreasing sleep difficulties (-0.64, 95%CI -0.86 to -0.43) were associated with a more pronounced decline in verbal memory when compared to constantly without sleep difficulties (-0.42, 95%CI -0.52 to -0.32) in post-retirement period. No statistically significant differences across sleep duration groups in cognitive function were observed. Conclusion: Increasing and decreasing sleep difficulties may be associated with accelerated decline in cognitive function during retirement transition and post-retirement.
Type: | Article |
---|---|
Title: | Association of sleep with cognitive function during retirement transition: The Whitehall II Study |
DOI: | 10.1093/sleep/zsac237 |
Publisher version: | https://doi.org/10.1093/sleep/zsac237 |
Language: | English |
Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
Keywords: | Sleep duration, Sleep difficulties, Sleep quality, Cognitive function |
UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Epidemiology and Public Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences |
URI: | https://discovery.ucl.ac.uk/id/eprint/10156546 |
Archive Staff Only
![]() |
View Item |