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Stress-dependent design and optimization methodology of gradient porous implant and application in femoral stem

Sun, Changning; Kang, Jianfeng; Wang, Ling; Jin, Zhongmin; Liu, Chaozong; Li, Dichen; (2022) Stress-dependent design and optimization methodology of gradient porous implant and application in femoral stem. Computer Methods in Biomechanics and Biomedical Engineering 10.1080/10255842.2022.2115291. (In press).

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Abstract

Gradient porous structure made by additive manufacturing (AM) technology is potential to improve the long-term stability of orthopaedic implants through bone ingrowth while maintaining mechanical safety. In this study, a parametrical optimization methodology for the customized gradient porous implants was developed based on a stress-dependent design algorithm. Clinical requirements and manufacturing capabilities of AM were considered in the design procedure. A femoral stem with a minimum bone loss proportion of 2.4% by optimizing the control parameters. This study provided a feasible and flexible design approach for the customized implant with gradient porous structure or material components.

Type: Article
Title: Stress-dependent design and optimization methodology of gradient porous implant and application in femoral stem
Location: England
DOI: 10.1080/10255842.2022.2115291
Publisher version: https://doi.org/10.1080/10255842.2022.2115291
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions.
Keywords: Gradient porous implant, elastic modulus, finite element analysis, customized implant, additive manufacturing
UCL classification: UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Ortho and MSK Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
URI: https://discovery.ucl.ac.uk/id/eprint/10156445
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