Omar, Jasmin;
Ponsford, Daniel;
Dreiss, Cecile A;
Lee, Tung-Chun;
Loh, Xian Jun;
(2022)
Supramolecular Hydrogels: Design Strategies and Contemporary Biomedical Applications.
Chemistry - An Asian Journal
, 17
(9)
, Article e202200081. 10.1002/asia.202200081.
Preview |
Text
Supramolecular Hydrogels- Design Strategies and Contemporary Biomedical Applications (accepted version).pdf - Accepted Version Download (2MB) | Preview |
Abstract
Self-assembly of supramolecular hydrogels is driven by dynamic, non-covalent interactions between molecules. Considerable research effort has been exerted to fabricate and optimise supramolecular hydrogels that display shear-thinning, self-healing, and reversibility, in order to develop materials for biomedical applications. This review provides a detailed overview of the chemistry behind the dynamic physicochemical interactions that sustain hydrogel formation (hydrogen bonding, hydrophobic interactions, ionic interactions, metal-ligand coordination, and host-guest interactions). Novel design strategies and methodologies to create supramolecular hydrogels are highlighted, which offer promise for a wide range of applications, specifically drug delivery, wound healing, tissue engineering and 3D bioprinting. To conclude, future prospects are briefly discussed, and consideration given to the steps required to ultimately bring these biomaterials into clinical settings.
| Type: | Article |
|---|---|
| Title: | Supramolecular Hydrogels: Design Strategies and Contemporary Biomedical Applications |
| Location: | Germany |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1002/asia.202200081 |
| Publisher version: | https://doi.org/10.1002/asia.202200081 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | Science & Technology, Physical Sciences, Chemistry, Multidisciplinary, Chemistry, biomedical applications, gels, molecular recognition, non-covalent interactions, self-assembly, supramolecular chemistry, PEPTIDE AMPHIPHILE VESICLES, SELF-ASSEMBLED HYDROGELS, ALPHA-CYCLODEXTRIN, NETWORK PROPERTIES, SUSTAINED-RELEASE, RECENT PROGRESS, HYBRID SYSTEM, DELIVERY, STRENGTH, TOUGH |
| UCL classification: | UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > MAPS Faculty Office > Institute for Materials Discovery UCL > Provost and Vice Provost Offices > UCL BEAMS UCL UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > MAPS Faculty Office |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10156244 |
Archive Staff Only
 |
View Item |
