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Advances in the Study of Magnesium Alloys and Their Use in Bone Implant Material

Zhi, Peixuan; Liu, Leixin; Chang, Jinke; Liu, Chaozong; Zhang, Qiliang; Zhou, Jian; Liu, Ziyu; (2022) Advances in the Study of Magnesium Alloys and Their Use in Bone Implant Material. Metals , 12 (9) , Article 1500. 10.3390/met12091500. Green open access

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Abstract

Magnesium and magnesium alloys have great application potential in the field of orthopaedics. Compared with traditional inorganic nonmetallic materials and medical polymer materials, magnesium alloys have many advantages, such as better strength, toughness, fatigue resistance, and easy processing. Its mechanical properties are suitable and controllable. It can meet the same elastic modulus, cell compatibility, and biodegradability as human cortical bone. There are also some drawbacks for biodegradability, as magnesium and its alloys, with their high degradation rate, can cause insufficient integrity of the mechanical properties. This paper summarises the research on magnesium and its magnesium alloy materials in the field of bone implantation, looking at what magnesium and its magnesium alloys are, the history of magnesium alloys in bone implant materials, the manufacturing of magnesium alloys, the mechanical properties of magnesium alloys, the bio-compatibility and clinical applications of magnesium alloys, the shortcomings, and the progress of research in recent years.

Type: Article
Title: Advances in the Study of Magnesium Alloys and Their Use in Bone Implant Material
Open access status: An open access version is available from UCL Discovery
DOI: 10.3390/met12091500
Publisher version: https://doi.org/10.3390/met12091500
Language: English
Additional information: © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).
Keywords: magnesium alloy; bone implant material; biomechanical properties; biocompatibility; biodegradability
UCL classification: UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Ortho and MSK Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Surgical Biotechnology
URI: https://discovery.ucl.ac.uk/id/eprint/10155954
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