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Mapping established psychopathology scales onto the Hierarchical Taxonomy of Psychopathology (HiTOP)

Wendt, Leon P; Jankowsky, Kristin; Zimmermann, Johannes; Schroeders, Ulrich; Nolte, Tobias; Fonagy, Peter; Montague, P Read; (2023) Mapping established psychopathology scales onto the Hierarchical Taxonomy of Psychopathology (HiTOP). Personality and Mental Health 10.1002/pmh.1566. (In press).

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Abstract

The Hierarchical Taxonomy of Psychopathology (HiTOP) organizes phenotypes of mental disorder based on empirical covariation, offering a comprehensive organizational framework from narrow symptoms to broader patterns of psychopathology. We argue that established self-report measures of psychopathology from the pre-HiTOP era should be systematically integrated into HiTOP to foster cumulative research and further the understanding of psychopathology structure. Hence, in this study, we mapped 92 established psychopathology (sub)scales onto the current HiTOP working model using data from an extensive battery of self-report assessments that was completed by community participants and outpatients (N = 909). A bifactor-(S-1) approach was used to model the p factor and five HiTOP spectra (i.e., internalizing, thought disorder, detachment, disinhibited externalizing, antagonistic externalizing) and this model was validated against personality disorder diagnoses as assessed by standardized interviews. We then located established scales within the taxonomy by estimating the extent to which scales reflected higher-level HiTOP dimensions. The analyses shed light on the location of established psychopathology scales in HiTOP, identifying pure markers and blends of HiTOP spectra, as well as pure markers of the p factor (i.e., scales assessing mentalizing impairment and suspiciousness/epistemic mistrust). We discuss implications of our results for psychopathology structure and its measurement

Type: Article
Title: Mapping established psychopathology scales onto the Hierarchical Taxonomy of Psychopathology (HiTOP)
DOI: 10.1002/pmh.1566
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Hierarchical Taxonomy of Psychopathology, self-report assessment, bifactor-(S-1) model
UCL classification: UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences > Clinical, Edu and Hlth Psychology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences
URI: https://discovery.ucl.ac.uk/id/eprint/10154802
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