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TB preventive treatment among pregnant women with HIV

DeAtley, T; Hamada, Y; Baddeley, A; Werner, P; Kanchar, A; Zignol, M; Rangaka, MX; (2022) TB preventive treatment among pregnant women with HIV. International Journal of Tuberculosis and Lung Disease , 26 (8) pp. 727-732. 10.5588/ijtld.21.0477. Green open access

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Abstract

BACKGROUND: The WHO recommends TB preventive treatment (TPT) for people living with HIV, including pregnant women. Uptake of this policy recommendation in this subpopulation and country alignment with WHO guidance is unclear.METHODS: We conducted a policy review in 38 WHO high TB and TB-HIV burden countries to assess if the uptake of TPT policy among pregnant women living with HIV was in line with the WHO´s 2018 Updated and Consolidated Guidelines for Programmatic Management for LTBI. Data sources included TB national guidelines and HIV/AIDS/ART national guidelines, complemented by results from a previous survey on policy uptake held at the WHO.RESULTS: Uptake of WHO policy to provide TB preventive treatment among women with HIV accessing antenatal care was moderate: 64% (23 of 36 countries) explicitly recommended at least one clinical guideline or policy recommendation on screening, testing or treatment of LTBI among pregnant women living with HIV. There was considerable variation between countries on the stages in pregnancy that TPT should be provided. Two countries (5%) provided clinical monitoring recommendations for pregnant women.CONCLUSIONS: There is moderate uptake of TPT policy for pregnant women with HIV. Failure to provide TPT as part of antenatal or prevention of mother-to-child services is a missed opportunity for TB control.

Type: Article
Title: TB preventive treatment among pregnant women with HIV
Location: France
Open access status: An open access version is available from UCL Discovery
DOI: 10.5588/ijtld.21.0477
Publisher version: https://doi.org/10.5588/ijtld.21.0477
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Acquired Immunodeficiency Syndrome, Female, HIV Infections, Humans, Infectious Disease Transmission, Vertical, Mass Screening, Pregnancy, Pregnant Women
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health > Infection and Population Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
URI: https://discovery.ucl.ac.uk/id/eprint/10154311
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