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Incidence of postural hypotension recorded in UK general practice: an electronic health records study

Bhanu, Cini; Petersen, Irene; Orlu, Mine; Davis, Daniel; Walters, Kate; (2023) Incidence of postural hypotension recorded in UK general practice: an electronic health records study. British Journal of General Practice , 73 (726) e9-e15. 10.3399/bjgp.2022.0111. Green open access

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Abstract

Background: Postural hypotension is a common condition associated with adverse outcomes in older adults. General practice plays an important role in identification. Aim: To examine i) the incidence of postural hypotension over the last decade in general practice and ii) how trends vary by age, sex, year, social deprivation. Design: Retrospective cohort study using electronic health records from IQVIA Medical Research Database (IMRD) between 2000 and 2018. Method: Patients from IMRD were included if they were aged at least 50 years. Incident postural hypotension was identified as a new (first) recording of a postural hypotension code. Recording of incident postural hypotension was estimated per 10,000 PYAR according to age, sex, year and social deprivation. Relative risk ratios were estimated by multivariable Poisson regression. A significant age/sex interaction was identified. Results: Of 2,911,260 patients, 24,973 had an electronic record indicating a new diagnosis of postural hypotension between 2008 and 2019. This was equivalent to 17.9 cases per 10,000 PYAR in men (95% CI 17.6-18.2) and 16.2 cases per 10,000 PYAR in women (95% CI 15.9-16.5). The rate of recorded postural hypotension increased with age, social deprivation and reduced between 2008 and 2018. The rate was higher in men compared with women, particularly in older age groups (>80 years). Conclusion: This is the first study to quantify incident recorded postural hypotension in general practice. The rate is lower than expected compared with studies in screened older populations. Future research should investigate benefits of routine screening of postural BP using standardised measures.

Type: Article
Title: Incidence of postural hypotension recorded in UK general practice: an electronic health records study
Open access status: An open access version is available from UCL Discovery
DOI: 10.3399/bjgp.2022.0111
Publisher version: https://doi.org/10.3399/bjgp.2022.0111
Language: English
Additional information: © The Authors. This article is Open Access: CC BY 4.0 licence (http://creativecommons.org/licences/by/4.0/).
Keywords: Postural hypotension, Large database research, Research methods, orthostatic hypotension
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Primary Care and Population Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
URI: https://discovery.ucl.ac.uk/id/eprint/10154236
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