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Epilepsy surgery for children and adolescents: evidence-based but underused

Cross, J Helen; Reilly, Colin; Gutierrez Delicado, Eva; Smith, Mary Lou; Malmgren, Kristina; (2022) Epilepsy surgery for children and adolescents: evidence-based but underused. The Lancet Child & Adolescent Health , 6 (7) pp. 484-494. 10.1016/S2352-4642(22)00098-0.

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Abstract

Paediatric epilepsy surgery is an increasingly used evidence-based management option with low risks for complications. Developments in neuroimaging techniques and other advanced diagnostics have widened the spectrum of children who could benefit from the procedure, and surgery is now considered a standard management approach for epilepsy. Available data indicate that early surgery improves outcomes. Despite these considerable advances, epilepsy surgery in children is still underused. In this Review, we summarise the indications, patient selection, principles of presurgical investigations, optimal timing, and types of epilepsy surgery. We also examine comprehensive outcomes after surgery, including seizure outcomes, complications, cognition, neurodevelopment, vocational outcome, and health-related quality of life of children and their parents. Successful epilepsy surgery could lead to improvement in all these areas. Children should, therefore, be referred early for evaluation in an appropriately competent centre.

Type: Article
Title: Epilepsy surgery for children and adolescents: evidence-based but underused
Location: England
DOI: 10.1016/S2352-4642(22)00098-0
Publisher version: https://doi.org/10.1016/S2352-4642(22)00098-0
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Adolescent, Child, Epilepsy, Humans, Neuroimaging, Patient Selection, Quality of Life, Seizures
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Neurosciences Dept
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
URI: https://discovery.ucl.ac.uk/id/eprint/10153305
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