UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

RADseq data reveal a lack of admixture in a mouse lemur contact zone contrary to previous microsatellite results

Yang, Ziheng; (2022) RADseq data reveal a lack of admixture in a mouse lemur contact zone contrary to previous microsatellite results. Proceedings of the Royal Society B: Biological Sciences , 289 , Article 20220596. 10.1098/rspb.2022.0596. Green open access

[thumbnail of Yang_rspb.2022.0596.pdf]
Preview
Text
Yang_rspb.2022.0596.pdf

Download (1MB) | Preview

Abstract

Microsatellites have been a workhorse of evolutionary genetic studies for decades and are still commonly in use for estimating signatures of genetic diversity at the population and species level across a multitude of taxa. Yet, the very high mutation rate of these loci is a double-edged sword, conferring great sensitivity at shallow levels of analysis (e.g. paternity analysis) but yielding considerable uncertainty for deeper evolutionary comparisons. For the present study, we used reduced representation genome-wide data (restriction site-associated DNA sequencing (RADseq)) to test for patterns of interspecific hybridization previously characterized using microsatellite data in a contact zone between two closely related mouse lemur species in Madagascar (Microcebus murinus and Microcebus griseorufus). We revisit this system by examining populations in, near, and far from the contact zone, including many of the same individuals that had previously been identified as hybrids with microsatellite data. Surprisingly, we find no evidence for admixed nuclear ancestry. Instead, re-analyses of microsatellite data and simulations suggest that previously inferred hybrids were false positives and that the program NEWHYBRIDS can be particularly sensitive to erroneously inferring hybrid ancestry. Combined with results from coalescent-based analyses and evidence for local syntopic co-occurrence, we conclude that the two mouse lemur species are in fact completely reproductively isolated, thus providing a new understanding of the evolutionary rate whereby reproductive isolation can be achieved in a primate.

Type: Article
Title: RADseq data reveal a lack of admixture in a mouse lemur contact zone contrary to previous microsatellite results
Open access status: An open access version is available from UCL Discovery
DOI: 10.1098/rspb.2022.0596
Publisher version: http://doi.org/10.1098/rspb.2022.0596
Language: English
Additional information: This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third-party material in this article are included in the Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
Keywords: RADseq, admixture, cryptic species, mouse lemurs, Madagascar, microsatellites
UCL classification: UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Genetics, Evolution and Environment
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
URI: https://discovery.ucl.ac.uk/id/eprint/10153118
Downloads since deposit
9Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item