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Steroids as treatment for glomerulonephritis: time for a rethink

Hendra, Heidy; Salama, Alan D; (2022) Steroids as treatment for glomerulonephritis: time for a rethink. Nephrology Dialysis Transplantation , 37 (7) pp. 1212-1217. 10.1093/ndt/gfaa267. Green open access

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Abstract

Glucocorticoids have been a cornerstone of treatment for inflammatory and autoimmune kidney diseases for almost 70 years, yet it is fair to say, we still do not know how 'best' to use them. Significant adverse events are associated with their continued use, which contribute to premature patient mortality. Steroid avoidance or minimization is possible and has been tested in various glomerular diseases, as a result of novel agents or innovative regimens using established therapeutics. It is now time to seriously address our use of steroids and educate physicians on better ways of managing inflammatory kidney diseases.

Type: Article
Title: Steroids as treatment for glomerulonephritis: time for a rethink
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1093/ndt/gfaa267
Publisher version: https://doi.org/10.1093/ndt/gfaa267
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Glomerulonephritis, IgA nephropathy, nephrotic syndrome, systemic lupus erythematosus, vasculitis
UCL classification: UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Renal Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
URI: https://discovery.ucl.ac.uk/id/eprint/10152127
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