Rogers, Priya;
Walker, Ieuan;
Yeung, Jason;
Khan, Abeera;
Gangi, Anmol;
Mobashwera, Behnaz;
Ayto, Robert;
... Von Stempel, Conrad; + view all
(2022)
Thrombus Distribution in Vaccine-induced immune thrombotic thrombocytopenia after ChAdOx1 nCov-19 Vaccination.
Radiology
, 305
(3)
pp. 590-596.
10.1148/radiol.220365.
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Abstract
This case series reports 40 patients (median age, 41 years [interquartile range (IQR) 32- 52, 22 men) with confirmed vaccine-induced immune thrombotic thrombocytopaenia after administration of their first ChAdOx1 nCov-19 (AstraZeneca) vaccine: 80% (n=32) developed symptoms within the first 14 days and 20% (n=8) within 14-28 days. The location and extent of thrombi were evaluated using CT, MRI and ultrasound. Of the 40, 73% (n=29) presented with neurological symptoms and had confirmed cerebral venous sinus thrombosis, 30% (n=12) had extension of their primary thrombus, and 20% (n=8) died. 83% of those who underwent additional imaging (25 of 30) had occult thrombosis.
| Type: | Article |
|---|---|
| Title: | Thrombus Distribution in Vaccine-induced immune thrombotic thrombocytopenia after ChAdOx1 nCov-19 Vaccination |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1148/radiol.220365 |
| Publisher version: | https://doi.org/10.1148/radiol.220365 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| UCL classification: | UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Department of Imaging UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10150079 |
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