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A step forward for LRRK2 inhibitors in Parkinson's disease

Lewis, Patrick A; (2022) A step forward for LRRK2 inhibitors in Parkinson's disease. Science Translational Medicine , 14 (648) , Article eabq7374. 10.1126/scitranslmed.abq7374. Green open access

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Abstract

A phase 1 clinical trial for kinase inhibitors targeting LRRK2 provides the foundation for testing the efficacy of LRRK2 kinase inhibitors in Parkinson’s disease.

Type: Article
Title: A step forward for LRRK2 inhibitors in Parkinson's disease
Open access status: An open access version is available from UCL Discovery
DOI: 10.1126/scitranslmed.abq7374
Publisher version: https://www.science.org/stoken/author-tokens/ST-54...
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Department of Neuromuscular Diseases
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
URI: https://discovery.ucl.ac.uk/id/eprint/10150053
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