UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Implantable cardioverter-defibrillators for hypertrophic cardiomyopathy: The Times They Are a-Changin'

Francia, Pietro; Olivotto, Iacopo; Lambiase, Pier D; Autore, Camillo; (2021) Implantable cardioverter-defibrillators for hypertrophic cardiomyopathy: The Times They Are a-Changin'. EP Europace , Article euab309. 10.1093/europace/euab309.

[thumbnail of Lambiase_ICDs for HCM Europace revision #1 final.pdf] Text
Lambiase_ICDs for HCM Europace revision #1 final.pdf
Access restricted to UCL open access staff until 31 December 2022.

Download (1MB)

Abstract

The implantable cardioverter-defibrillator (ICD) is a life-saving therapy in patients with hypertrophic cardiomyopathy (HCM) at high risk of sudden cardiac death. The heterogeneity of clinical scenarios in HCM and the availability of ICDs with distinct characteristics emphasizes the need for selecting the right device for the right patient. There is growing awareness that unnecessarily complex devices can lead to short- and long-term complications without adding significant clinical benefits. Young patients have the greatest potential years of life gained from the ICD but are also most exposed to device-related complications. This increases the complexity of decision-making of ICD prescription in these often otherwise well patients in whom device selection should be tailored to preserve survival benefit without introducing morbidity. In the light of the multiple clinical phenotypes characterizing HCM, the present article offers evidence-based perspectives helpful in predicting the individual impact of the ICD and choosing the most appropriate device.

Type: Article
Title: Implantable cardioverter-defibrillators for hypertrophic cardiomyopathy: The Times They Are a-Changin'
Location: England
DOI: 10.1093/europace/euab309
Publisher version: https://doi.org/10.1093/europace/euab309
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Science & Technology, Life Sciences & Biomedicine, Cardiac & Cardiovascular Systems, Cardiovascular System & Cardiology, Hypertrophic cardiomyopathy, Implantable cardioverter-defibrillator, Sudden cardiac death, SUDDEN CARDIAC DEATH, ALCOHOL SEPTAL ABLATION, AUTOMATED SCREENING TOOL, 2020 AHA/ACC GUIDELINE, RISK STRATIFICATION, AMERICAN-COLLEGE, EUROPEAN-SOCIETY, DUAL-CHAMBER, TASK-FORCE, VENTRICULAR TACHYARRHYTHMIAS
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Clinical Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
URI: https://discovery.ucl.ac.uk/id/eprint/10149690
Downloads since deposit
1Download
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item