UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

A Journey Through Genetics to Biology

Van Heyningen, Veronica; (2022) A Journey Through Genetics to Biology. Annual Review of Genomics and Human Genetics , 23 10.1146/annurev-genom-010622-095109. (In press).

[thumbnail of annurev-genom-010622-095109.pdf] Text
annurev-genom-010622-095109.pdf - Published Version
Access restricted to UCL open access staff

Download (6MB)

Abstract

Although my engagement with human genetics emerged gradually, and sometimes serendipitously, it has held me spellbound for decades. Without my teachers, students, postdocs, colleagues, and collaborators, I would not be writing this review of my scientific adventures. Early gene and disease mapping was a satisfying puzzle-solving exercise, but building biological insight was my main goal. The project trajectory was hugely influenced by the evolutionarily conserved nature of the implicated genes and by the pace of progress in genetic technologies. The rich detail of clinical observations, particularly in eye disease, makes humans an excellent model, especially when complemented by the use of multiple other animal species for experimental validation. The contributions of collaborators and rivals also influenced our approach. We are very fortunate to work in this era of unprecedented progress in genetics and genomics. Expected final online publication date for the Annual Review of Genomics and Human Genetics, Volume 23 is October 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

Type: Article
Title: A Journey Through Genetics to Biology
Location: United States
DOI: 10.1146/annurev-genom-010622-095109
Publisher version: https://doi.org/10.1146/annurev-genom-010622-09510...
Language: English
Additional information: This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Ophthalmology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL
URI: https://discovery.ucl.ac.uk/id/eprint/10149345
Downloads since deposit
0Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item