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Towards optimum smoking cessation interventions during pregnancy: a household model to explore cost‐effectiveness

Saygın Avşar, Tuba; Jackson, Louise; Barton, Pelham; Jones, Matthew; McLeod, Hugh; (2022) Towards optimum smoking cessation interventions during pregnancy: a household model to explore cost‐effectiveness. Addiction , 117 (10) pp. 2707-2719. 10.1111/add.15955. Green open access

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Abstract

Background and Aims: Previous economic evaluations of smoking cessation interventions for pregnant women are limited to single components, which do not in isolation offer sufficient potential impact to address smoking cessation targets. To inform the development of more appropriate complex interventions, we (1) describe the development of the Economics of Smoking in Pregnancy: Household (ESIP.H) model for estimating the life-time cost-effectiveness of smoking cessation interventions aimed at pregnant women and (2) use a hypothetical case study to demonstrate how ESIP. H can be used to identify the characteristics of optimum smoking cessation interventions. / Methods: The hypothetical intervention was based on current evidence relating to component elements, including financial incentives, partner smoking, intensive behaviour change support, cigarettes consumption, and duration of support to 12 months post-partum. ESIP. H was developed to assess the life-time health and cost impacts of multi-component interventions compared with standard National Health Service (NHS) care in England. ESIP. H considers cigarettes consumption, partner smoking and some health conditions (e.g. obesity) that were not included in previous models. The Markov model’s parameters were estimated based on published literature, expert judgement and evidence-based assumptions. The hypothetical intervention was evaluated from an NHS perspective. / Results: The hypothetical intervention was associated with an incremental gain in quitters (mother and partner) at 12 months postpartum of 249 (95% confidence intervals [CIs] 195 to 304) per 1000 pregnant smokers. Over the long-term, it had an incremental negative cost of £193 (CIs -£779 to £344) and it improved health, with a 0.50 (CIs 0.36 to 0.69) increase in quality-adjusted life years (QALYs) for mothers, partners and offspring, with a 100% probability of being cost-effective. / Conclusions: The Economics of Smoking in Pregnancy: Household model for estimating cost-effectiveness of smoking cessation interventions aimed at pregnant women found that a hypothetical smoking cessation intervention would greatly extend reach, reduce smoking, and be cost-effective.

Type: Article
Title: Towards optimum smoking cessation interventions during pregnancy: a household model to explore cost‐effectiveness
Open access status: An open access version is available from UCL Discovery
DOI: 10.1111/add.15955
Publisher version: https://doi.org/10.1111/add.15955
Language: English
Additional information: This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. See: http://creativecommons.org/licenses/by-nc-nd/4.0/
Keywords: Smoking Cessation, Tobacco, Pregnancy, Economic Evaluation, Cost-Effective, Cost-Utility, Health Inequality
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Applied Health Research
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
URI: https://discovery.ucl.ac.uk/id/eprint/10149338
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