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Editorial: Biofabrication and Biopolymeric Materials Innovation for Musculoskeletal Tissue Engineering cook

Cooke, Megan; Rosenzweig, Derek; Liu, Chaozong; Ghorbani, Farnaz; (2022) Editorial: Biofabrication and Biopolymeric Materials Innovation for Musculoskeletal Tissue Engineering cook. Frontiers in Bioengineering and Biotechnology , 10 , Article 909577. 10.3389/fbioe.2022.909577. Green open access

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Abstract

The human musculoskeletal system provides form, support, stability, and movement to the body. It is made up of the bones of the skeleton, muscles, cartilage, tendons, ligaments, joints, and other connective tissues. The primary functions of the musculoskeletal system include supporting the body, allowing motion, and protecting vital organs. The skeletal portion of the system serves as the main storage system for calcium and phosphorus and contains critical components of the hematopoietic system (Li and Niu, 2020). Musculoskeletal Disorders (MSDs) include injuries and diseases that primarily affect the movement of the human body. They are characterized by pain and limitations in mobility, dexterity, and overall level of functioning, reducing patients’ ability to work and maintain a good quality of life. A recent analysis of Global Burden of Disease data showed that approximately 1.71 billion people globally have musculoskeletal conditions (Woolf and Pfleger, 2003). MSDs such as osteoarthritis, rheumatoid arthritis, psoriatic arthritis, gout, and ankylosing spondylitis affect joints (McInnes and Schett, 2011; Loeser et al., 2012; Litwic et al., 2013); osteoporosis, osteopenia and associated fragility fractures, as well as traumatic fractures, affect bones (Florencio-Silva et al., 2015); sarcopenia affects muscles, and back and neck pain affect the spine of the human body.

Type: Article
Title: Editorial: Biofabrication and Biopolymeric Materials Innovation for Musculoskeletal Tissue Engineering cook
Open access status: An open access version is available from UCL Discovery
DOI: 10.3389/fbioe.2022.909577
Publisher version: https://doi.org/10.3389/fbioe.2022.909577
Language: English
Additional information: © 2022 Cooke, Rosenzweig, Liu and Ghorbani. This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/).
Keywords: bioprinting, biofabrication, biomaterials, biopolymers, tissue engineering, musculoskeletal
UCL classification: UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Ortho and MSK Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
URI: https://discovery.ucl.ac.uk/id/eprint/10149093
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