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Opinion Piece: The case for establishing a minimal medication alternative for psychosis and schizophrenia

Cooper, RE; Mason, JP; Calton, T; Richardson, J; Moncrieff, J; (2021) Opinion Piece: The case for establishing a minimal medication alternative for psychosis and schizophrenia. Psychosis , 13 (3) pp. 276-285. 10.1080/17522439.2021.1930119. Green open access

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Abstract

The development of severe mental health conditions is strongly linked to our environments, particularly experiences of trauma and adversity. However treatments for severe mental health conditions are often primarily biomedical, centred around medication. For people diagnosed with schizophrenia or psychosis, this is antipsychotic medication. Although antipsychotics have been found to reduce symptoms and risk of relapse, some patients derive little benefit from these drugs, and they can lead to severe adverse effects. Subsequently, a high proportion of people do not want to take antipsychotics and request an alternative. Yet in the UK and in many countries there are currently no guidelines for stopping antipsychotics or formal treatment alternatives, despite such alternatives being available in some countries. For example, in Norway and Vermont (USA), in response to pressure from service user organisations, governments have mandated the establishment of “minimal medication” services. We examine whether everyone with a psychotic condition needs long-term antipsychotic treatment and evidence for alternative models of care. We recommend that healthcare providers should be encouraged to develop a psychosocial treatment package for people with psychosis or schizophrenia that provides a realistic possibility of minimising antipsychotic exposure.

Type: Article
Title: Opinion Piece: The case for establishing a minimal medication alternative for psychosis and schizophrenia
Open access status: An open access version is available from UCL Discovery
DOI: 10.1080/17522439.2021.1930119
Publisher version: https://doi.org/10.1080/17522439.2021.1930119
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Social Sciences, Science & Technology, Life Sciences & Biomedicine, Psychology, Clinical, Psychiatry, Psychology, Psychosis, schizophrenia, minimal medication, psychosocial treatments, antipsychotic reduction or discontinuation, alternative treatments, ANTIPSYCHOTIC MEDICATION, 1ST-EPISODE PSYCHOSIS, FOLLOW-UP, DISCONTINUATION, PEOPLE, DRUGS, NEUROLEPTICS, METAANALYSIS, MORTALITY, SYMPTOMS
UCL classification: UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL
URI: https://discovery.ucl.ac.uk/id/eprint/10148335
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