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Comparison of generic and specific instruments to assess the quality of life in patients with melasma

Meneguin, Silmara; Mourao, Ioana Bitencourt; Pollo, Camila Fernandes; Miot, Helio Amante; Garuzi, Miriane; de Oliveira, Cesar; (2022) Comparison of generic and specific instruments to assess the quality of life in patients with melasma. BMC Medical Research Methodology , 22 (1) , Article 117. 10.1186/s12874-022-01599-5. Green open access

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Abstract

Objective: To compare the psychometric performance of a generic and specific instruments in assessing melasma-related quality of life. Methods: A cross-sectional study was conducted with 150 patients with melasma attending an outpatient dermatology clinic of a public hospital in São Paulo state, Brazil. Data were collected using a questionnaire containing sociodemographic and clinical data as well as the generic WHOQOL-BREF, and the dermatological-specific Skindex-16 and HRQ-Melasma. Results: The overall internal consistency of the domains of the three instruments was ≥ 0.7. A strong positive correlation was identified between the Skindex-16 and HRQ-Melasma domains (0.68-0.78). Item-response theory showed that most Skindex-16 and HRQ-Melasma domains were more informative than WHOQOL-BREF. Conclusion: The three instruments for assessing QOL tested presented good psychometric performance, with satisfactory internal consistency values. Only the two dermatological instruments, however, demonstrated a strong correlation between the domains that assess social, emotional, and functional aspects of QOL, indicating that both were able to identify impairments in other QOL dimensions in addition to the physical domain.

Type: Article
Title: Comparison of generic and specific instruments to assess the quality of life in patients with melasma
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1186/s12874-022-01599-5
Publisher version: https://doi.org/10.1186/s12874-022-01599-5
Language: English
Additional information: Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visithttp://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
Keywords: Melasma, Quality of life, Psychometry, Questionnaire, WORLD-HEALTH-ORGANIZATION, PSYCHIATRIC MORBIDITY, QUESTIONNAIRE, VALIDATION, WHOQOL, VERSION
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Epidemiology and Public Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
URI: https://discovery.ucl.ac.uk/id/eprint/10148245
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