Hamer, Mark;
Blodgett, Joanna M;
Stamatakis, Emmanuel;
(2022)
Dose-response association between step count and cardiovascular disease risk markers in middle aged adults.
Scandinavian Journal of Medicine and Science in Sports
10.1111/sms.14173.
(In press).
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Abstract
Several step-based daily targets have been widely circulated, but there is a lack of empirical population-based evidence to support such guidance. We examined dose-response associations between step count and classical CVD risk markers (glycated haemoglobin, high density lipoprotein cholesterol, triglycerides, C-reactive protein) in 4,665 adults (aged 46 yr; 51.4% female) in a cross-sectional study. Step counts were measured from a thigh mounted accelerometer (activPAL) worn over 7 days. The shape of the dose response curve for most risk markers was 'L-shaped', with linear risk reduction up to around 10,000 steps a day. Controlling for stepping intensity did not materially alter our results.
| Type: | Article |
|---|---|
| Title: | Dose-response association between step count and cardiovascular disease risk markers in middle aged adults |
| Location: | Denmark |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1111/sms.14173 |
| Publisher version: | https://doi.org/10.1111/sms.14173 |
| Language: | English |
| Additional information: | © 2022 The Authors. Scandinavian Journal of Medicine & Science In Sports published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
| Keywords: | cardiovascular disease, epidemiology, exercise, physical activity, population |
| UCL classification: | UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10147580 |
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