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Delivering Endothelial Keratoplasty Grafts: Modern Day Transplant Devices

Parekh, Mohit; Romano, Vito; Hassanin, Kareem; Testa, Valeria; Wongvisavavit, Rintra; Ferrari, Stefano; Willoughby, Colin; ... Levis, Hannah; + view all (2022) Delivering Endothelial Keratoplasty Grafts: Modern Day Transplant Devices. Current Eye Research , 47 (4) pp. 493-504. 10.1080/02713683.2021.2016852. Green open access

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Abstract

PURPOSE: To summarize the graft loading, transporting and delivery devices used for endothelial keratoplasty (EK). METHODS: A literature search of electronic databases was performed. RESULTS: New techniques and devices have been introduced and implemented to prepare, load, transport and transplant the grafts for EK. The advantages are not only limited to the surgical theatre but also widely spread across the eye banking field. Investigation of advanced materials and designs have been rapidly growing with continuous evolution in the field of eye banking and corneal transplantation. Innovative techniques and modern devices have been evaluated to reduce the endothelial cell loss and increase the precision of the transplant in order to benefit both surgeons and the patients. CONCLUSIONS: It is extremely important to reduce any potential wastage and optimize the use of every available donor cornea due to the limited availability of healthy cadaveric donor corneas required for transplants. As a result, the use of pre-cut and pre-loaded grafts supplied by the eye banks in calibrated devices have been gaining momentum. Innovation in the field of bioengineering for the development of new devices that facilitate excellent clinical outcomes along with reduction in learning curve has shown promising results.

Type: Article
Title: Delivering Endothelial Keratoplasty Grafts: Modern Day Transplant Devices
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1080/02713683.2021.2016852
Publisher version: https://doi.org/10.1080/02713683.2021.2016852
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions.
Keywords: Cornea, endothelial keratoplasty, DSAEK, DMEK, devices, glides
UCL classification: UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Ophthalmology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL
URI: https://discovery.ucl.ac.uk/id/eprint/10147440
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