UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Dynamics of cortical and corticomuscular connectivity during planning and execution of visually guided steps in humans

Spedden, Meaghan E; Beck, Mikkel M; West, Timothy O; Farmer, Simon F; Nielsen, Jens B; Lundbye-Jensen, Jesper; (2023) Dynamics of cortical and corticomuscular connectivity during planning and execution of visually guided steps in humans. Cerebral Cortex , 33 (2) pp. 258-277. 10.1093/cercor/bhac066. Green open access

[thumbnail of Spedden_stepping_accepted.pdf]
Preview
Text
Spedden_stepping_accepted.pdf

Download (1MB) | Preview

Abstract

The cortical mechanisms underlying the act of taking a step-including planning, execution, and modification-are not well understood. We hypothesized that oscillatory communication in a parieto-frontal and corticomuscular network is involved in the neural control of visually guided steps. We addressed this hypothesis using source reconstruction and lagged coherence analysis of electroencephalographic and electromyographic recordings during visually guided stepping and 2 control tasks that aimed to investigate processes involved in (i) preparing and taking a step and (ii) adjusting a step based on visual information. Steps were divided into planning, initiation, and execution phases. Taking a step was characterized by an upregulation of beta/gamma coherence within the parieto-frontal network during planning followed by a downregulation of alpha and beta/gamma coherence during initiation and execution. Step modification was characterized by bidirectional modulations of alpha and beta/gamma coherence in the parieto-frontal network during the phases leading up to step execution. Corticomuscular coherence did not exhibit task-related effects. We suggest that these task-related modulations indicate that the brain makes use of communication through coherence in the context of large-scale, whole-body movements, reflecting a process of flexibly fine-tuning inter-regional communication to achieve precision control during human stepping.

Type: Article
Title: Dynamics of cortical and corticomuscular connectivity during planning and execution of visually guided steps in humans
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1093/cercor/bhac066
Publisher version: https://doi.org/10.1093/cercor/bhac066
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: coherence, EEG, EMG, stepping, walking
UCL classification: UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Imaging Neuroscience
URI: https://discovery.ucl.ac.uk/id/eprint/10147379
Downloads since deposit
20Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item