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A review of corneal biomechanics: Mechanisms for measurement and the implications for refractive surgery

Marshall, John; Wilson, Abby; (2020) A review of corneal biomechanics: Mechanisms for measurement and the implications for refractive surgery. Indian Journal of Ophthalmology , 68 (12) pp. 2679-2690. 10.4103/ijo.ijo_2146_20. Green open access

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Abstract

Detailed clinical assessment of corneal biomechanics has the potential to revolutionize the ophthalmic industry through enabling quicker and more proficient diagnosis of corneal disease, safer and more effective surgical treatments, and the provision of customized and optimized care. Despite these wide-ranging benefits, and an outstanding clinical need, the provision of technology capable of the assessment of corneal biomechanics in the clinic is still in its infancy. While laboratory-based technologies have progressed significantly over the past decade, there remain significant gaps in our knowledge regarding corneal biomechanics and how they relate to shape and function, and how they change in disease and after surgical intervention. Here, we discuss the importance, relevance, and challenges associated with the assessment of corneal biomechanics and review the techniques currently available and underdevelopment in both the laboratory and the clinic.

Type: Article
Title: A review of corneal biomechanics: Mechanisms for measurement and the implications for refractive surgery
Open access status: An open access version is available from UCL Discovery
DOI: 10.4103/ijo.ijo_2146_20
Publisher version: https://doi.org/10.4103/ijo.ijo_2146_20
Language: English
Additional information: © 2022 Indian Journal of Ophthalmology. This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution‑NonCommercial‑ShareAlike 4.0 License (https://creativecommons.org/licenses/by-nc-sa/4.0/).
Keywords: Biomechanics, corneal crosslinking, customized treatment, diagnostic screening, keratoconus, refractive surgery
UCL classification: UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Mechanical Engineering
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL
URI: https://discovery.ucl.ac.uk/id/eprint/10146898
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