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Few-shot image segmentation for cross-institution male pelvic organs using registration-assisted prototypical learning

Li, Yiwen; Fu, Yunguan; Yang, Qianye; Min, Zhe; Yan, Wen; Huisman, Henkjan; Prisacariu, Victor Adrian; ... Hu, Yipeng; + view all (2022) Few-shot image segmentation for cross-institution male pelvic organs using registration-assisted prototypical learning. In: Proceedings of the IEEE International Symposium on Biomedical Imaging (ISBI) 2022. IEEE: Kolkata, India. (In press). Green open access

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Abstract

The ability to adapt medical image segmentation networks for a novel class such as an unseen anatomical or pathological structure, when only a few labelled examples of this class are available from local healthcare providers, is sought-after. This potentially addresses two widely recognised limitations in deploying modern deep learning models to clinical practice, expertise-and-labour-intensive labelling and cross-institution generalisation. This work presents the first 3D few-shot interclass segmentation network for medical images, using a labelled multi-institution dataset from prostate cancer patients with eight regions of interest. We propose an image alignment module registering the predicted segmentation of both query and support data, in a standard prototypical learning algorithm, to a reference atlas space. The built-in registration mechanism can effectively utilise the prior knowledge of consistent anatomy between subjects, regardless whether they are from the same institution or not. Experimental results demonstrated that the proposed registration-assisted prototypical learning significantly improved segmentation accuracy (p-values<0.01) on query data from a holdout institution, with varying availability of support data from multiple institutions. We also report the additional benefits of the proposed 3D networks with 75% fewer parameters and an arguably simpler implementation, compared with existing 2D few-shot approaches that segment 2D slices of volumetric medical images.

Type: Proceedings paper
Title: Few-shot image segmentation for cross-institution male pelvic organs using registration-assisted prototypical learning
Event: IEEE International Symposium on Biomedical Imaging (ISBI) 2022
Open access status: An open access version is available from UCL Discovery
DOI: 10.1109/ISBI52829.2022.9761453
Publisher version: http://dx.doi.org/10.1109/ISBI52829.2022.9761453
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: eess.IV, eess.IV, cs.CV
UCL classification: UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL
URI: https://discovery.ucl.ac.uk/id/eprint/10146183
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