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Measuring change in inclusion body myositis: clinical assessments versus imaging.

Alfano, Lindsay N; Focht Garand, Kendrea L; Malandraki, Georgia A; Salam, Sharfaraz; Machado, Pedro M; Dimachkie, Mazen M; (2022) Measuring change in inclusion body myositis: clinical assessments versus imaging. Clinical and Experimental Rheumatology , 40 (2) pp. 404-413. Green open access

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Abstract

Sporadic inclusion body myositis (sIBM) is a heterogeneous progressive inflammatory muscle disease impacting skeletal muscles in the head, neck, and limbs. Use of valid, reliable, sensitive, and standardised clinical and paraclinical outcome assessments (COA) are critical to inform both proactive clinical care and clinical trial design. Here we review clinical and imaging methods used to quantify muscle strength, size, or function in sIBM, and discuss their application to clinical practice and use in clinical trials. Considerations for future work to validate measures in this population are also discussed.

Type: Article
Title: Measuring change in inclusion body myositis: clinical assessments versus imaging.
Location: Italy
Open access status: An open access version is available from UCL Discovery
Publisher version: https://www.clinexprheumatol.org/abstract.asp?a=18...
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions.
Keywords: Diagnostic Imaging, Humans, Muscle Strength, Muscle, Skeletal, Myositis, Inclusion Body
UCL classification: UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Department of Neuromuscular Diseases
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
URI: https://discovery.ucl.ac.uk/id/eprint/10145409
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