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Eyes, the window on psychosis?

Shoham, Natalie; Cooper, Claudia; (2022) Eyes, the window on psychosis? BJPsych Open , 8 (2) , Article e44. 10.1192/bjo.2022.16. Green open access

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Abstract

Much has been written on the theory that congenital blindness might protect against schizophrenia, but proof remains elusive. It has been suggested that visual ability might be associated with schizophrenia in a bell-shaped distribution, with both lifelong absent and perfect vision being protective. Alternatively, ocular aberrations and schizophrenia may share an aetiology. Any neuronal pathology implicated in schizophrenia could affect the retina, since it is an embryological extension of the brain. The retina is more amenable to direct imaging than other parts of the central nervous system and may give unique insights into schizophrenia-associated neuropathology. It is also possible that psychosis causes visual impairment: people with psychotic illnesses are probably not accessing optical care optimally and have higher levels of risk factors for visual loss.

Type: Article
Title: Eyes, the window on psychosis?
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1192/bjo.2022.16
Publisher version: https://doi.org/10.1192/bjo.2022.16
Language: English
Additional information: © The Author(s), 2022. Published by Cambridge University Press on behalf of the Royal College of Psychiatrists. This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/).
Keywords: Visual impairment, congenital blindness, psychosis, schizophrenia, visual acuity
UCL classification: UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL
URI: https://discovery.ucl.ac.uk/id/eprint/10143555
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