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Progressive hemispheric atrophy in HIV: A Rasmussen’s-like variant of CD8 encephalitis?

Thom, Maria; (2022) Progressive hemispheric atrophy in HIV: A Rasmussen’s-like variant of CD8 encephalitis? Neuropathology and Applied Neurobiology , 48 (4) , Article e12794. 10.1111/nan.12794. Green open access

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Abstract

We report two cases of progressive lateralising encephalopathy in adult patients with treated HIV in the absence of opportunistic infection or vasculitis. One case was characterised by CD8 cortical infiltrates and was steroid responsive and may represent a variant of CD8 encephalitis. The other case presented with focal seizures and episodes of status epilepticus and pathology showed severe cortical atrophy with features reminiscent of the chronic phase of Rasmussen's encephalitis.

Type: Article
Title: Progressive hemispheric atrophy in HIV: A Rasmussen’s-like variant of CD8 encephalitis?
Open access status: An open access version is available from UCL Discovery
DOI: 10.1111/nan.12794
Publisher version: https://doi.org/10.1111/nan.12794
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Clinical and Experimental Epilepsy
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
URI: https://discovery.ucl.ac.uk/id/eprint/10142832
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