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Bringing social context into global biomedical HIV cure-related research: An urgent call to action

Miall, A; McLellan, R; Dong, K; Ndung'u, T; Saberi, P; Sauceda, JA; Dubé, K; (2021) Bringing social context into global biomedical HIV cure-related research: An urgent call to action. Journal of Virus Eradication 10.1016/j.jve.2021.100062. (In press). Green open access

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Abstract

Advances in science have ushered in a wave of new potential curative and control strategies for HIV that could eliminate the current requirement for life-long antiretroviral therapy (ART) for people living with HIV (PLWH). In this article, we argue that it is critical to consider social contexts in the development of HIV cure trial protocols. The biological and behavioral risk factors for HIV acquisition by study participants are inseparable from the social context in which these participants live. The article discusses an example of a cohort established to further HIV cure research that included social context, called the FRESH Acute HIV study, which combines a sociostructural intervention while conducting HIV prevention, treatment and cure-related research in Durban, South Africa. We make an urgent call to action to include sociobehavioral components as instrumental in future HIV cure trials in global context.

Type: Article
Title: Bringing social context into global biomedical HIV cure-related research: An urgent call to action
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.jve.2021.100062
Publisher version: https://doi.org/10.1016/j.jve.2021.100062
Language: English
Additional information: This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. The images or other third-party material in this article are included in the Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit https://creativecommons.org/licenses/by-nc-nd/4.0/
Keywords: Social sciences, HIV cure research, Women, South Africa
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Infection and Immunity
URI: https://discovery.ucl.ac.uk/id/eprint/10142441
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