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Persistent orbital inflammation following complete excision of deep dermoid cysts

Thaung, C; Wilde, C; Vahdani, K; Rose, GE; (2022) Persistent orbital inflammation following complete excision of deep dermoid cysts. Orbit 10.1080/01676830.2022.2025855. (In press). Green open access

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Abstract

Piecemeal excision of dermoid cysts carries the risk of implanting epithelial fragments into orbital fat, which is well recognized to continue secreting oily debris, inciting chronic, often granulomatous inflammation. The authors present the clinical and histological details for two patients with persistent lipogranulomatous inflammation for years after piecemeal excision of deep orbital dermoid cysts, in the absence of any residual epithelium. The importance of copious saline lavage – to ‘float-out” and reduce microscopic lipid droplets – is also emphasised.

Type: Article
Title: Persistent orbital inflammation following complete excision of deep dermoid cysts
Open access status: An open access version is available from UCL Discovery
DOI: 10.1080/01676830.2022.2025855
Publisher version: https://doi.org/10.1080/01676830.2022.2025855
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Dermoid; cyst; orbit; excision; inflammation; persistent; extracellular; lipids
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Ophthalmology
URI: https://discovery.ucl.ac.uk/id/eprint/10142174
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