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A Statistical DOI Estimation Algorithm for a SiPM-Based Clinical SPECT Insert

DrAdda, I; Morahan, AJ; Carminati, M; Erlandsson, K; Ljungberg, M; Hutton, BF; Fiorini, C; (2022) A Statistical DOI Estimation Algorithm for a SiPM-Based Clinical SPECT Insert. IEEE Transactions on Radiation and Plasma Medical Sciences 10.1109/TRPMS.2022.3140411. (In press). Green open access

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Abstract

A prototype clinical brain SPECT insert has been designed for use in simultaneous SPECT/MRI. The system utilises novel slit-slat collimators which, like pinhole collimators, suffers from parallax errors due to the large incident angle of photons. A statistical algorithm has been developed to determine the depth-of-interaction (DOI) with a view to improving image performance. The importance of DOI correction was demonstrated using Monte Carlo simulation. This simulation also indicated that 4 DOI layers (3×1.5 mm+3.5 mm) may be sufficient. The improvement in event localisation was demonstrated on a single detector before implementing the algorithm on the full clinical prototype where some limitations in event localisation in layers close to the readout plane were observed. Nevertheless DOI enabled the rejection of poorly localised events with improved resolution in reconstructed line sources.

Type: Article
Title: A Statistical DOI Estimation Algorithm for a SiPM-Based Clinical SPECT Insert
Open access status: An open access version is available from UCL Discovery
DOI: 10.1109/TRPMS.2022.3140411
Publisher version: https://doi.org/10.1109/TRPMS.2022.3140411
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Department of Imaging
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/10142134
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