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Is perfect the enemy of good? Weighing the evidence for biparametric MRI in prostate cancer

Cole, AP; Langbein, BJ; Giganti, F; Fennessy, FM; Tempany, CM; Emberton, M; (2022) Is perfect the enemy of good? Weighing the evidence for biparametric MRI in prostate cancer. The British Journal of Radiology , 95 (1131) , Article 20210840. 10.1259/bjr.20210840. Green open access

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Abstract

The role of multiparametric MRI in diagnosis, staging and treatment planning for prostate cancer is well established. However there remain several challenges to widespread adoption. One such challenge is the duration and cost the examination. Abbreviated exams omitting contrast enhanced sequences may help address this challenge. In this review, we will discuss the rationale for biparametric MRI (bpMRI) for detection and characterization of clinically significant prostate cancer prior to biopsy and synthesize the published literature. We will weigh up the advantages and disadvantages to this approach and lay out a conceptual cost/benefit analysis regarding adoption of bpMRI.

Type: Article
Title: Is perfect the enemy of good? Weighing the evidence for biparametric MRI in prostate cancer
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1259/bjr.20210840
Publisher version: https://doi.org/10.1259/bjr.20210840
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
URI: https://discovery.ucl.ac.uk/id/eprint/10139332
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