Busani, S;
Bedini, A;
Biagioni, E;
Serio, L;
Tonelli, R;
Meschiari, M;
Franceschini, E;
... Modena Covid-19 Working Group (MoCo19); + view all
(2021)
Two Fatal Cases of Acute Liver Failure Due to HSV-1 Infection in COVID-19 Patients Following Immunomodulatory Therapies.
Clinical Infectious Diseases
, 73
(1)
e252-e255.
10.1093/cid/ciaa1246.
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Abstract
We report two fatal cases of acute liver failure secondary to herpes simplex virus 1 infection in COVID-19 patients, following tocilizumab and corticosteroid therapy. Screening for and prompt recognition of herpes simplex virus 1 reactivation in these patients, undergoing immunomodulatory treatment, may have potentially relevant clinical consequences.
| Type: | Article |
|---|---|
| Title: | Two Fatal Cases of Acute Liver Failure Due to HSV-1 Infection in COVID-19 Patients Following Immunomodulatory Therapies |
| Location: | United States |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1093/cid/ciaa1246 |
| Publisher version: | https://doi.org/10.1093/cid/ciaa1246 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | COVID-19, Herpes Simplex, Herpesvirus 1, Human, Humans, Immunomodulation, Liver Failure, Acute, SARS-CoV-2 |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health > Infection and Population Health |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10138427 |
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