Albert, J;
Jarman, A;
Kamikouchi, A;
Keder, A;
(2020)
Drosophila as a Model for Hearing and Deafness.
In: Fritzsch, B, (ed.)
The Senses: A Comprehensive Reference.
(pp. 985-1004).
Elsevier
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Abstract
As evidenced not least by its age-related breakdown in humans, hearing is a delicate physiological process. Across the animal kingdom, ears operate at the borders of the physically, and the biologically, possible. Human biomedical need, evolutionary convergence, as well as mechanistic similarities are strong arguments for exploiting the scientific power of the fruit fly Drosophila melanogaster to understand hearing - and ultimately fight deafness. This chapter provides an overview of the fly's auditory system and highlights the various ways by which Drosophila studies can inform, and advance, human hearing research.
| Type: | Book chapter |
|---|---|
| Title: | Drosophila as a Model for Hearing and Deafness |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/B978-0-12-809324-5.24216-8 |
| Publisher version: | https://doi.org/10.1016/B978-0-12-809324-5.24216-8 |
| Language: | English |
| Additional information: | This version is the version of record. For information on re-use, please refer to the publisher's terms and conditions. |
| Keywords: | Age-related hearing loss (ARHL); Antennal hearing; Auditory homeostasis; Auditory transduction; Chordotonal organ; Congenital hearing loss; Ciliogenesis; Deafness; Diptera; Drosophila model; Hearing loss; Johnston's organ; Noise-induced hearing loss (NIHL); Scolopidia; Sound processing |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > The Ear Institute |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10137853 |
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