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Membrane trafficking: Retrofusion as an escape route out of the endosome

Eden, ER; Futter, CE; (2021) Membrane trafficking: Retrofusion as an escape route out of the endosome. Current Biology , 31 (17) R1037-R1040. 10.1016/j.cub.2021.07.055. Green open access

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Abstract

Intraluminal vesicles accumulate within the endosomal lumen before lysosomal delivery or extracellular release. A new study reports the development of an elegant assay showing that these vesicles can escape from the endosomal lumen by ‘back-fusion’ or ‘retrofusion’ with the endosomal limiting membrane.

Type: Article
Title: Membrane trafficking: Retrofusion as an escape route out of the endosome
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.cub.2021.07.055
Publisher version: https://doi.org/10.1016/j.cub.2021.07.055
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Ophthalmology
URI: https://discovery.ucl.ac.uk/id/eprint/10137611
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