Mackle, EC;
Coote, JM;
Carr, E;
Little, CD;
van Soest, G;
Desjardins, AE;
(2021)
Fibre optic intravascular measurements of blood flow: A review.
Sensors and Actuators A: Physical
, 332
(2)
, Article 113162. 10.1016/j.sna.2021.113162.
(In press).
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Abstract
Fibre optic sensors are well suited to measuring fluid flow in many contexts, and recently there has been burgeoning interest in their application to direct, invasive measurement of blood flow within human vasculature. Depending on the sensing method used and assumptions made, these intravascular measurements of blood flow can provide information about local blood velocity, volumetric flow, and flow-derived parameters. Fibre optic sensors can be readily integrated into medical devices, which are positioned into arteries and veins to obtain measurements that are inaccessible or cumbersome using non-invasive imaging modalities. Measurements of flow within coronary arteries is a particularly promising application of fibre optic sensing; recent studies have demonstrated the clinical utility of certain flow-based parameters, such as the coronary flow reserve (CFR) and the index of microcirculatory resistance (IMR). In this review, research and development of fibre optic flow sensors relevant to intravascular flow measurements are reviewed, with a particular focus on biomedical clinical translation.
| Type: | Article |
|---|---|
| Title: | Fibre optic intravascular measurements of blood flow: A review |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.sna.2021.113162 |
| Publisher version: | https://doi.org/10.1016/j.sna.2021.113162 |
| Language: | English |
| Additional information: | This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0). |
| Keywords: | Blood flow, Intravascular measurement, Coronary physiology |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10137237 |
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